Diphenidol Has No Actual Broad Antiemetic Activity in Dogs and Ferrets

• Main Authors: Hiroe Nakayama (Author), Hisashi Yamakuni (Author), Aya Nakayama (Author), Yasue Maeda (Author), Katsunori Imazumi (Author), Masahiko Matsuo (Author), Seitaro Mutoh (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous studies showed that diphenidol was effective on emetogens-induced pica, eating of non-nutritive substances, in rats, a model analogous to emesis in other species. We evaluated the actual antiemetic activity of diphenidol against four emetic stimuli in the dog and ferret, animals that posses...