Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats

• 主要な著者: Dan Zhu (著者), Tingting Fan (著者), Xinyue Huo (著者), Jian Cui (著者), Chi Wai Cheung (著者), Zhengyuan Xia (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2019-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Diabetic neuropathic pain (DNP) is a common and serious complication of diabetic patients. The pathogenesis of DNP is largely unclear. The proinflammation proteins, CXCR4, and TNF-α play critical roles in the development of pain, while their relative roles in the development of DNP and especially it...