Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa <i>via</i> an In Vitro Model

Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa <i>via</i> an In Vitro Model

Modulation of drug transporter activity at mucosal sites of HIV-1 transmission may be exploited to optimize retention of therapeutic antiretroviral drug concentrations at target submucosal CD4+ T cells. Previously, we showed that darunavir was a substrate for the P-glycoprotein efflux drug transport...

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Main Authors: Constandinos Carserides (Author), Kieron Smith (Author), Marta Zinicola (Author), Abhinav Kumar (Author), Magda Swedrowska (Author), Carlo Scala (Author), Gary Cameron (Author), Zoe Riches (Author), Francesco Iannelli (Author), Gianni Pozzi (Author), Georgina L. Hold (Author), Ben Forbes (Author), Charles Kelly (Author), Karolin Hijazi (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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