Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

• Main Authors: Jana Gerstmeier (Author), Julia Seegers (Author), Finja Witt (Author), Birgit Waltenberger (Author), Veronika Temml (Author), Judith M. Rollinger (Author), Hermann Stuppner (Author), Andreas Koeberle (Author), Daniela Schuster (Author), Oliver Werz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Lipid mediators (LMs) comprise bioactive metabolites of polyunsaturated fatty acids, including pro-inflammatory prostaglandins (PGs), thromboxanes (TXs), and leukotrienes (LTs), as well as specialized pro-resolving mediators (SPMs). They are essentially biosynthesized via cyclooxygenas...