PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway

• Главные авторы: Xiaoyan Yang (Автор), Min A (Автор), Tana Gegen (Автор), Badema Daoerji (Автор), Yue Zheng (Автор), Aiming Wang (Автор)
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• Опубликовано: BMC, 2024-01-01T00:00:00Z.
• Предметы: article
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Abstract Background Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphologic features, and PCOS is associated with infertility. PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) has been shown to regulate A...