A Multicentric, Open-Label, Randomized, Comparative Clinical Trial of Two Different Doses of Expanded hBM-MSCs Plus Biomaterial versus Iliac Crest Autograft, for Bone Healing in Nonunions after Long Bone Fractures: Study Protocol

• Main Authors: Enrique Gómez-Barrena (Author), Norma G. Padilla-Eguiluz (Author), Cristina Avendaño-Solá (Author), Concepción Payares-Herrera (Author), Ana Velasco-Iglesias (Author), Ferran Torres (Author), Philippe Rosset (Author), Florian Gebhard (Author), Nicola Baldini (Author), Juan C. Rubio-Suarez (Author), Eduardo García-Rey (Author), José Cordero-Ampuero (Author), Javier Vaquero-Martin (Author), Francisco Chana (Author), Fernando Marco (Author), Javier García-Coiradas (Author), Pedro Caba-Dessoux (Author), Pablo de la Cuadra (Author), Philippe Hernigou (Author), Charles-Henri F (Author), François Gouin (Author), Didier Mainard (Author), Jean Michel Laffosse (Author), Miriam Kalbitz (Author), Ingo Marzi (Author), Norbert Südkamp (Author), Ulrich Stöckle (Author), Gabriela Ciapetti (Author), Davide Maria Donati (Author), Luigi Zagra (Author), Ugo Pazzaglia (Author), Guido Zarattini (Author), Rodolfo Capanna (Author), Fabio Catani (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ORTHOUNION is a multicentre, open, comparative, three-arm, randomized clinical trial (EudraCT number 2015-000431-32) to compare the efficacy, at one and two years, of autologous human bone marrow-derived expanded mesenchymal stromal cell (hBM-MSC) treatments versus iliac crest autograft (ICA) to enh...