Pluripotency markers are differentially induced by IGF1 and bFGF in cells from patients' lesions of large/giant congenital melanocytic nevi

• Main Authors: Dipanjan Basu (Author), Cláudia M. Salgado (Author), Janki R. Patel (Author), Joie Zabec (Author), Ryan M. Hoehl (Author), Bruce Bauer (Author), Miguel Reyes-Múgica (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Factors regulating transcription of pluripotency genes in congenital nevo-melanocytes are not known. Nevo-melanocytes belong somewhere in-between the ends of a spectrum where the normal epidermal melanocyte represents one end and a melanoma cell with multiple genetic abnormalities represent...