Quantification of Differential Metabolites in Dried Blood Spots Using Second-Tier Testing for SCADD/IBDD Disorders Based on Large-Scale Newborn Screening in a Chinese Population

• Main Authors: Wei Zhou (Author), Heng Cai (Author), Huizhong Li (Author), Zhe Ji (Author), Maosheng Gu (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• 主题: article
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Background: Although newborn screening (NBS) for metabolic defects using the marker butyl carnitine (C4) combined with the C4-to-acetylcarnitine ratio is adequate, the incorporation of novel parameters may improve differential testing for these disorders without compromising sensitivity.Methods: Ana...