Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives

• Główni autorzy: Francesco Saccoliti (Autor), Gabriella Angiulli (Autor), Giovanni Pupo (Autor), Luca Pescatori (Autor), Valentina Noemi Madia (Autor), Antonella Messore (Autor), Gianni Colotti (Autor), Annarita Fiorillo (Autor), Luigi Scipione (Autor), Marina Gramiccia (Autor), Trentina Di Muccio (Autor), Roberto Di Santo (Autor), Roberta Costi (Autor), Andrea Ilari (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The study presented here aimed at identifying a new class of compounds acting against Leishmania parasites, the causative agent of Leishmaniasis. For this purpose, the thioether derivatives of our in-house library have been evaluated in whole-cell screening assays in order to determine their in vitr...