Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

• المؤلفون الرئيسيون: Stine Harloff-Helleberg (مؤلف), Lies A. L. Fliervoet (مؤلف), Mathias Fanø (مؤلف), Mechthild Schmitt (مؤلف), Maxim Antopolski (مؤلف), Arto Urtti (مؤلف), Hanne Mørck Nielsen (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Oral drug delivery is an attractive noninvasive alternative to injectables. However, oral delivery of biopharmaceuticals is highly challenging due to low stability during transit in the gastrointestinal tract (GIT), resulting in low systemic bioavailability. Thus, novel formulation strategies are es...