An age‐dependent mathematical model of neurofilament trafficking in healthy conditions

• Main Authors: Alessio Paris (Author), Pranami Bora (Author), Silvia Parolo (Author), Michael Monine (Author), Xiao Tong (Author), Satish Eraly (Author), Eric Masson (Author), Toby Ferguson (Author), Alexander McCampbell (Author), Danielle Graham (Author), Enrico Domenici (Author), Ivan Nestorov (Author), Luca Marchetti (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Neurofilaments (Nfs) are the major structural component of neurons. Their role as a potential biomarker of several neurodegenerative diseases has been investigated in past years with promising results. However, even under physiological conditions, little is known about the leaking of Nfs fr...