In Vitro Drug Release, Permeability, and Structural Test of Ciprofloxacin-Loaded Nanofibers

• Main Authors: Luca Éva Uhljar (Author), Sheng Yuan Kan (Author), Norbert Radacsi (Author), Vasileios Koutsos (Author), Piroska Szabó-Révész (Author), Rita Ambrus (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanofibers of the poorly water-soluble antibiotic ciprofloxacin (CIP) were fabricated in the form of an amorphous solid dispersion by using poly(vinyl pyrrolidone) as a polymer matrix, by the low-cost electrospinning method. The solubility of the nanofibers as well as their in vitro diffusion were r...