Unraveling DDIT4 in the VDR-mTOR pathway: a novel target for drug discovery in diabetic kidney disease

• Main Authors: Hai-tao Lu (Author), Yuan-yuan Jiao (Author), Tian-yu Yu (Author), Jing-xuan Shi (Author), Jing-wei Tian (Author), Gu-ming Zou (Author), Lin Liu (Author), Li Zhuo (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Introduction:Diabetic kidney disease (DKD) necessitates innovative therapeutic strategies. This study delves into the role of DNA damage-inducing transcription factor 4 (DDIT4) within the VDR-mTOR pathway, aiming to identify a novel target for DKD drug discovery.Methods:Transcriptome data from the G...