Involvement of Peripheral Mechanism in the Verapamil-Induced Potentiation of Morphine Analgesia in Mice

• Main Authors: Norifumi Shimizu (Author), Shiroh Kishioka (Author), Takehiko Maeda (Author), Yohji Fukazawa (Author), Yoshihiro Dake (Author), Chizuko Yamamoto (Author), Masanobu Ozaki (Author), Hiroyuki Yamamoto (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Morphine's analgesic actions are thought to be mediated through both the central and peripheral nervous systems. L-type calcium channel blockers have been reported to potentiate the analgesic effects of morphine, but the locus of this interaction is not known. In this experiment, we examined th...