Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils

• 主要な著者: André M. Cantin (著者), Cristine Ouellet (著者), Alexandre Cloutier (著者), Patrick P. McDonald (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Neutrophil killing of bacteria is mediated by oxidative and non-oxidative mechanisms. Oxidants are generated through the NADPH oxidase complex, whereas antimicrobial proteins and peptides rank amongst non-oxidative host defenses. Mucus hypersecretion, deficient hydration and poor clearance from the...