Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils

• मुख्य लेखकों: André M. Cantin (लेखक), Cristine Ouellet (लेखक), Alexandre Cloutier (लेखक), Patrick P. McDonald (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Neutrophil killing of bacteria is mediated by oxidative and non-oxidative mechanisms. Oxidants are generated through the NADPH oxidase complex, whereas antimicrobial proteins and peptides rank amongst non-oxidative host defenses. Mucus hypersecretion, deficient hydration and poor clearance from the...