Daptomycin-Impregnated PMMA Cement against Vancomycin-Resistant Germs: Dosage, Handling, Elution, Mechanical Stability, and Effectiveness

• Main Authors: Martina Humez (Author), Eugen Domann (Author), Kai M. Thormann (Author), Christian Fölsch (Author), Rainer Strathausen (Author), Sebastian Vogt (Author), Volker Alt (Author), Klaus-Dieter Kühn (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The number of periprosthetic joint infections caused by vancomycin-resistant pathogens is increasing. Currently, no PMMA cement is commercially available to cover VRE. Daptomycin shows promising results in treating infection, offering a good safety profile and a reduced risk of developin...