Implications of Antigen Selection on T Cell-Based Immunotherapy

Many immunotherapies rely on CD8+ effector T cells to recognize and kill cognate tumor cells. These T cell-based immunotherapies include adoptive cell therapy, such as CAR T cells or transgenic TCR T cells, and anti-cancer vaccines which expand endogenous T cell populations. Tumor mutation burden an...

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Main Authors: Faye A. Camp (Author), Jill E. Slansky (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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