Implications of Antigen Selection on T Cell-Based Immunotherapy
Many immunotherapies rely on CD8+ effector T cells to recognize and kill cognate tumor cells. These T cell-based immunotherapies include adoptive cell therapy, such as CAR T cells or transgenic TCR T cells, and anti-cancer vaccines which expand endogenous T cell populations. Tumor mutation burden an...
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MDPI AG,
2021-09-01T00:00:00Z.
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A1234.567 |
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