Analysis of efficacy of SGLT2 inhibitors using semi-mechanistic model

• Main Authors: Oleg eDemin Jr (Author), Tatiana eYakovleva (Author), Dmitry eKolobkov (Author), Oleg eDemin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal sodium-dependent glucose co-transporter 2 (SGLT2) is one of the most promising targets for the treatment of type 2 diabetes. Two SGLT2 inhibitors, dapagliflozin and canagliflozin, have already been approved for use in USA and Europe; several additional compounds are also being developed for th...