Perforating dermatosis in a patient receiving azathioprine

• Main Authors: Emiliano Grillo (Author), Sergio Vano-Galván (Author), Carmen Moreno (Author), Pedro Jaén (Author)
• Format: Knjiga
• Izdano: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Azathioprine (AZA) is an imidazole derivative of mercaptopurine. It antagonizes purine metabolism, and it may inhibit synthesis of DNA, RNA, and proteins. The 6-thioguanine nucleotides appear to mediate the majority of AZAs immunosuppressive and toxic effects. While cutaneous adverse side-effects ar...