Anaplastic lymphoma kinase-positive pulmonary inflammatory myofibroblastic tumor with sarcomatous morphology and distant metastases: An unusual histomorphology and behavior

• Главные авторы: Bhawna Sethi (Автор), Trupti Pai (Автор), Abhishek Allam (Автор), Sridhar Epari (Автор)
• Формат: ‌
• Опубликовано: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Inflammatory myofibroblastic tumor (IMT), an intermediate-grade neoplasm of myofibroblastic/fibroblastic differentiation, occurs commonly in children and young adults. It is characterized by anaplastic lymphoma kinase (ALK) gene rearrangement and overexpression of ALK-protein. However, aggressive be...