Outcomes of BRCA pre-implantation genetic testing according to the parental mutation origin: a cohort study

• Главные авторы: Ilana Weizel (Автор), Tal Shavit (Автор), Yulia Shuli (Автор), Chana Adler Lazarovich (Автор), Rivka Halevi (Автор), Tal Ben Ari (Автор), Shira Yaacobi-Artzi (Автор), Yaakov Bentov (Автор), Baruch Feldman (Автор), Anat Hershko Klement (Автор)
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• Опубликовано: BMC, 2024-01-01T00:00:00Z.
• Предметы: article
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Abstract Background The process of gamete formation and early embryonic development involves rapid DNA replication, chromosome segregation and cell division. These processes may be affected by mutations in the BRCA1/2 genes. The aim of this study was to evaluate BRCA mutation inheritance and its eff...