Outcomes of BRCA pre-implantation genetic testing according to the parental mutation origin: a cohort study

• Main Authors: Ilana Weizel (Author), Tal Shavit (Author), Yulia Shuli (Author), Chana Adler Lazarovich (Author), Rivka Halevi (Author), Tal Ben Ari (Author), Shira Yaacobi-Artzi (Author), Yaakov Bentov (Author), Baruch Feldman (Author), Anat Hershko Klement (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The process of gamete formation and early embryonic development involves rapid DNA replication, chromosome segregation and cell division. These processes may be affected by mutations in the BRCA1/2 genes. The aim of this study was to evaluate BRCA mutation inheritance and its eff...