AGEs promote atherosclerosis by increasing LDL transcytosis across endothelial cells via RAGE/NF-κB/Caveolin-1 pathway

• Main Authors: Meng Shu (Author), Wenzhuo Cheng (Author), Xiong Jia (Author), Xiangli Bai (Author), Ying Zhao (Author), Yajing Lu (Author), Lin Zhu (Author), Yan Zhu (Author), Li Wang (Author), Yan Shu (Author), Yi Song (Author), Si Jin (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective To elucidate the mechanism whereby advanced glycation end products (AGEs) accelerate atherosclerosis (AS) and to explore novel therapeutic strategies for atherosclerotic cardiovascular disease. Methods and results The effect of AGEs on low-density lipoprotein (LDL) transcytosis ac...