Artemisinin derivative DHA27 enhances the antibacterial effect of aminoglycosides against Pseudomonas aeruginosa by inhibiting mRNA expression of aminoglycoside-modifying enzymes

• मुख्य लेखकों: Nuoyan Wang (लेखक), Xuemin Chen (लेखक), Jing Luo (लेखक), Fei Deng (लेखक), Fuguo Shi (लेखक), Qin Wu (लेखक), Yasi Huang (लेखक), Qin Ouyang (लेखक), Rongxin Qin (लेखक), Hong Zhou (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Bacterial resistance is becoming increasingly serious, the present study aimed to investigate the mechanism of antibacterial sensitization effect of DHA27 combined with tobramycin in tobramycin-resistant Pseudomonas aeruginosa (PA). We found that DHA27 combined with aminoglycosides had an antibacter...