Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy

• المؤلفون الرئيسيون: Haibin Wu (مؤلف), Liyu Zhang (مؤلف), Zeen Zhu (مؤلف), Chenxi Ding (مؤلف), Shengquan Chen (مؤلف), Ruiping Liu (مؤلف), Huafeng Fan (مؤلف), Yang Chen (مؤلف), Hui Li (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...