Effect of cyclosporin A on respiratory viral replication in fully differentiated ex vivo human airway epithelia

• Main Authors: Louise Bondeelle (Author), Song Huang (Author), Samuel Constant (Author), Sophie Clément (Author), Maud Salmona (Author), Jérôme Le Goff (Author), Anne Bergeron (Author), Caroline Tapparel (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cyclosporin A (CsA), an immunosuppressive drug used in transplant recipients, inhibits graft rejection by binding to cyclophilins and competitively inhibiting calcineurin. While concerns about respiratory infections in immunosuppressed patients exist, contradictory data emerged during the C...