Efficient Ocular Delivery of VCP siRNA via Reverse Magnetofection in RHO P23H Rodent Retina Explants

• Auteurs principaux: Merve Sen (Auteur), Marco Bassetto (Auteur), Florent Poulhes (Auteur), Olivier Zelphati (Auteur), Marius Ueffing (Auteur), Blanca Arango-Gonzalez (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The use of synthetic RNA for research purposes as well as RNA-based therapy and vaccination has gained increasing importance. Given the anatomical seclusion of the eye, small interfering RNA (siRNA)-induced gene silencing bears great potential for targeted reduction of pathological gene expression t...