Real-World Data and Budget Impact Analysis (BIA): Evaluation of a Targeted Next-Generation Sequencing Diagnostic Approach in Two Orthopedic Rare Diseases

• Ngā kaituhi matua: Elena Pedrini (Author), Antonella Negro (Author), Eugenio Di Brino (Author), Valentina Pecoraro (Author), Camilla Sculco (Author), Elisabetta Abelli (Author), Maria Gnoli (Author), Armando Magrelli (Author), Luca Sangiorgi (Author), Americo Cicchetti (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Objective: Next-generation sequencing (NGS) technology, changing the diagnostic approach, has become essential in clinical settings, and its adoption by public health laboratories is now the practice. Despite this, as technological innovations, its intake requires an evaluation of both the clinical...