Effects of Lapatinib on HER2-Positive and HER2-Negative Canine Mammary Carcinoma Cells Cultured In Vitro

• Main Authors: Antonio Fernando Leis-Filho (Author), Patrícia de Faria Lainetti (Author), Priscila Emiko Kobayashi (Author), Carlos Eduardo Fonseca-Alves (Author), Renée Laufer-Amorim (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HER2 is a prognostic and predictive marker widely used in breast cancer. Lapatinib is a tyrosine kinase inhibitor that works by blocking the phosphorylation of the receptor HER2. Its use is related to relatively good results in the treatment of women with HER2+ breast cancer. Thus, this study aimed...