In Silico Prediction of Binding Affinities of Hybrid Molecules of Benzothiazole Linked with Hydroxamic Acid by Disulfide Bond and Certain Linkers with HDAC8 Enzyme

A new hybrid molecule of Benzothiazole cross-linked with hydroxamic acid through an amino acid or aminoalkanoic acid were synthesised. All the synthesized hybrid molecules (1-5) were subjected to molecular docking studies to evaluate their binding affinities with histone deacetylase enzyme (HDAC8, P...

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Main Authors: Mayssam Hazem (Author), Shakir M. Alwan (Author)
Format: Book
Published: College of Pharmacy / Mustansiriyah University, 2024-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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