In Silico Prediction of Binding Affinities of Hybrid Molecules of Benzothiazole Linked with Hydroxamic Acid by Disulfide Bond and Certain Linkers with HDAC8 Enzyme
A new hybrid molecule of Benzothiazole cross-linked with hydroxamic acid through an amino acid or aminoalkanoic acid were synthesised. All the synthesized hybrid molecules (1-5) were subjected to molecular docking studies to evaluate their binding affinities with histone deacetylase enzyme (HDAC8, P...
Saved in:
Main Authors: | Mayssam Hazem (Author), Shakir M. Alwan (Author) |
---|---|
Format: | Book |
Published: |
College of Pharmacy / Mustansiriyah University,
2024-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
In Silico Prediction of Binding Affinities of Hybrid Molecules of Benzothiazole cross-linked with Hydroxamic acid by certain linkers
by: yazen alqaysi, et al.
Published: (2024) -
In silico studies on modified hydroxamic acid and valporic acid as potential inhibitors for HDAC2
by: Naresh Kandakatla, et al.
Published: (2013) -
In silco studies on modified hydroxamic acid and valporic acid as potential inhibitors for HDAC2
by: Naresh Kandakatla, et al.
Published: (2013) -
Hydroxamic acid - A novel molecule for anticancer therapy
by: Dilipkumar Pal, et al.
Published: (2012) -
In Silico Profiling of Histone Deacetylase 8 Inhibitory Activity: A Computational Analysis of Novel Dipeptide-Based Compounds Cross-Linked with Hydroxamic Acid
by: omer mohammed ammash, et al.
Published: (2024)