BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis

• Những tác giả chính: Ran Deng (Tác giả), Yan Wang (Tác giả), Yanhong Bu (Tác giả), Hong Wu (Tác giả)
• Định dạng: Sách
• Được phát hành: BMC, 2022-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Abstract Background Hypoxia is one of the important characteristics of synovial microenvironment in rheumatoid arthritis (RA), and plays an important role in synovial hyperplasia. In terms of cell survival, fibroblast-like synovial cells (FLSs) are relatively affected by hypoxia. In contrast, fibrob...