Screening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the 'homology modelling-virtual screening-molecular docking-affinity assay-activity evaluation' method

• Main Authors: Wei Quan (Author), Yuan Wang (Author), Yu-han Chen (Author), Qing Shao (Author), Yang-ze Gong (Author), Jie-wen Hu (Author), Wei-hai Liu (Author), Zi-jun Wu (Author), Jie Wang (Author), Shan-bo Ma (Author), Xiao-qiang Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Salvia miltiorrhizae Bunge (Lamiaceae) is a traditional Chinese medicine (TCM) for the treatment of 'thoracic obstruction'. Transient receptor potential canonical channel 1 (TRPC1) is a important target for myocardial injury treatment.Objective This work screens the active...