Betulinic Acid Alleviates Spleen Oxidative Damage Induced by Acute Intraperitoneal Exposure to T-2 Toxin by Activating Nrf2 and Inhibiting MAPK Signaling Pathways

• Main Authors: Li Kong (Author), Lijuan Zhu (Author), Xianglian Yi (Author), You Huang (Author), Haoqiang Zhao (Author), Yazhi Chen (Author), Zhihang Yuan (Author), Lixin Wen (Author), Jing Wu (Author), Jine Yi (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

T-2 toxin, which is mainly produced by specific strains of <i>Fusarium</i> in nature, can induce immunotoxicity and oxidative stress, resulting in immune organ dysfunction and apoptosis. Betulinic acid (BA), a pentacyclic triterpenoids from nature plants, has been demonstrated to possess...