Functional biomarker signatures of circulating T-cells and its association with distinct clinical status of leprosy patients and their respective household contacts

• Main Authors: Pedro Henrique Ferreira Marçal (Author), Rafael Silva Gama (Author), Lorena Bruna Pereira de Oliveira (Author), Olindo Assis Martins-Filho (Author), Roberta Olmo Pinheiro (Author), Euzenir Nunes Sarno (Author), Milton Ozório Moraes (Author), Lucia Alves de Oliveira Fraga (Author)
• Format: Book
• Published: BMC, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Leprosy is a chronic infectious disease classified into two subgroups for therapeutic purposes: paucibacillary (PB) and multibacillary (MB), closely related to the host immune responses. In this context it is noteworthy looking for immunological biomarkers applicable as complemen...