⁶⁸Ga-Radiolabeling and Pharmacological Characterization of a Kit-Based Formulation of the Gastrin-Releasing Peptide Receptor (GRP-R) Antagonist RM2 for Convenient Preparation of [⁶⁸Ga]Ga-RM2

• Main Authors: Adrien Chastel (Author), Delphine Vimont (Author), Stephane Claverol (Author), Marion Zerna (Author), Sacha Bodin (Author), Mathias Berndt (Author), Stéphane Chaignepain (Author), Elif Hindié (Author), Clément Morgat (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: [⁶⁸Ga]Ga-RM2 is a potent Gastrin-Releasing Peptide-receptor (GRP-R) antagonist for imaging prostate cancer and breast cancer, currently under clinical evaluation in several specialized centers around the world. Targeted radionuclide therapy of GRP-R-expressing tumo...