Application of probabilistic methods to address variability and uncertainty in estimating risks for non-cancer health effects

• Main Authors: Greylin H. Nielsen (Author), Wendy J. Heiger-Bernays (Author), Jonathan I. Levy (Author), Roberta F. White (Author), Daniel A. Axelrad (Author), Juleen Lam (Author), Nicholas Chartres (Author), Dimitri Panagopoulos Abrahamsson (Author), Swati D. G. Rayasam (Author), Rachel M. Shaffer (Author), Lauren Zeise (Author), Tracey J. Woodruff (Author), Gary L. Ginsberg (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Human health risk assessment currently uses the reference dose or reference concentration (RfD, RfC) approach to describe the level of exposure to chemical hazards without appreciable risk for non-cancer health effects in people. However, this "bright line" approach assumes that t...