Safety of linezolid in patients with decreased renal function and trough monitoring: a systematic review and meta-analysis

• Main Authors: Xiaoxi Liu (Author), Mari Aoki (Author), Sumika Osa (Author), Chihiro Ito (Author), Reika Saiki (Author), Tomoya Nagai (Author), Yuki Enoki (Author), Kazuaki Taguchi (Author), Kazuaki Matsumoto (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Linezolid causes hematological toxicity, mostly thrombocytopenia, which leads to treatment discontinuation and failure. Recent studies revealed that during linezolid therapy, the incidence of treatment-related hematological toxicity is significantly higher in patients with decrea...