Topiramate Reprofiling for the Attenuation of Cadmium-Induced Testicular Impairment in Rats: Role of NLRP3 Inflammasome and AMPK/mTOR-Linked Autophagy

• Main Authors: Hany H. Arab (Author), Hayat A. Abd El Aal (Author), Shuruq E. Alsufyani (Author), Azza A. K. El-Sheikh (Author), El-Shaimaa A. Arafa (Author), Ahmed M. Ashour (Author), Ahmed M. Kabel (Author), Ahmed H. Eid (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Topiramate, a promising drug classically used for the management of neurological disorders including epilepsy and migraine, has demonstrated marked anti-inflammatory and anti-apoptotic actions in murine models of cardiac post-infarction inflammation, wound healing, and gastric/intestinal injury. How...