High expression levels and the C3435T SNP of the ABCB1 gene are associated with lower survival in adult patients with acute myeloblastic leukemia in Mexico City

Abstract Background Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by different genetic alterations that cause changes in the normal mechanisms of differentiation, which are associated with chemoresistance. The ABCB1 gene is part of a family of ATP-binding casse...

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Glavni autori: Irma Olarte Carrillo (Autor), Anel Irais García Laguna (Autor), Adrián De la Cruz Rosas (Autor), Christian Omar Ramos Peñafiel (Autor), Juan Collazo Jaloma (Autor), Adolfo Martínez Tovar (Autor)
Format: Knjiga
Izdano: BMC, 2021-10-01T00:00:00Z.
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