Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis.

• Main Authors: Anandharaman Veerapathran (Author), Gajalakshmi Dakshinamoorthy (Author), Munirathinam Gnanasekar (Author), Maryada Venkata Rami Reddy (Author), Ramaswamy Kalyanasundaram (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lymphatic filarial parasites survive within the lymphatic vessels for years despite the complex immune environment surrounding them. Parasites possibly accomplish this by adopting various immunomodulatory strategies, which include release of glutathione-S-transferases (GSTs) that counteract the oxid...