Role of APE1/Ref-1 in hydrogen peroxide-induced apoptosis in human renal HK-2 cells

• Main Authors: Ha Yeon Kim (Author), Jung Sun Park (Author), Byeong Hwa Jeon (Author), Hong Sang Choi (Author), Chang Seong Kim (Author), Seong Kwon Ma (Author), Soo Wan Kim (Author), Eun Hui Bae (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multipotent protein that plays essential roles in cellular responses to oxidative stress. Methods To examine the role of APE1/Ref-1 in ischemia-reperfusion (I/R) injuries and hydrogen peroxide (H2O2)-induced renal tubul...