Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

• Главные авторы: Chris K. Hewson (Автор), Alexander Capraro (Автор), Sharon L. Wong (Автор), Elvis Pandzic (Автор), Ling Zhong (Автор), Bentotage S. M. Fernando (Автор), Nikhil T. Awatade (Автор), Gene Hart-Smith (Автор), Renee M. Whan (Автор), Shane R. Thomas (Автор), Adam Jaffe (Автор), Wallace J. Bridge (Автор), Shafagh A. Waters (Автор)
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• Опубликовано: MDPI AG, 2020-11-01T00:00:00Z.
• Предметы: article
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Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...