Biocompatible PLGA-Mesoporous Silicon Microspheres for the Controlled Release of BMP-2 for Bone Augmentation

• Main Authors: Silvia Minardi (Author), Joseph S. Fernandez-Moure (Author), Dongmei Fan (Author), Matthew B. Murphy (Author), Iman K. Yazdi (Author), Xuewu Liu (Author), Bradley K. Weiner (Author), Ennio Tasciotti (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone morphogenetic protein-2 (BMP-2) has been demonstrated to be one of the most vital osteogenic factors for bone augmentation. However, its uncontrolled administration has been associated with catastrophic side effects, which compromised its clinical use. To overcome these limitations, we aimed at...