Design and encapsulation of anticancer dual HSP27 and HER2 inhibitor into low density lipoprotein to target ovarian cancer cells

Tumor cells overexpress low-density lipoprotein (LDL) receptors (LDL-r). Hence, LDL is proposed as a targeting shuttle of anticancer drugs. Therefore, the objective of this study was to synthesize a dual inhibitor of heat shock protein 27 (HSP27) and human epidermal growth factor receptor 2 (HER2) c...

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Autors principals: Laila J. Alhadad (Autor), Gamaleldin I. Harisa (Autor), Fars K. Alanazi (Autor)
Format: Llibre
Publicat: Elsevier, 2020-04-01T00:00:00Z.
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