The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection

• Main Authors: Vincenzo Torraca (Author), Chao Cui (Author), Ralf Boland (Author), Jan-Paul Bebelman (Author), Astrid M. van der Sar (Author), Martine J. Smit (Author), Marco Siderius (Author), Herman P. Spaink (Author), Annemarie H. Meijer (Author)
• Format: Book
• Published: The Company of Biologists, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The recruitment of leukocytes to infectious foci depends strongly on the local release of chemoattractant mediators. The human CXC chemokine receptor 3 (CXCR3) is an important node in the chemokine signaling network and is expressed by multiple leukocyte lineages, including T cells and macrophages....