Procyanidin B2 enhances anti-inflammatory responses of periodontal ligament cells by inhibiting the dominant negative pro-inflammatory isoforms of peroxisome proliferator-activated receptor γ

• Hauptverfasser: Tadahiro Yamamoto (VerfasserIn), Hang Yuan (VerfasserIn), Shigeki Suzuki (VerfasserIn), Eiji Nemoto (VerfasserIn), Masahiro Saito (VerfasserIn), Satoru Yamada (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2024-07-01T00:00:00Z.
• Schlagworte: article
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Background/purpose: Periodontal breakdown in periodontitis is exacerbated by pro-inflammatory responses of periodontal stromal cells such as periodontal ligament fibroblasts (PDLFs). Procyanidin B2 (PB2) is a ligand of the peroxisome proliferator-activated receptor (PPARγ). Herein, we investigated t...