RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3' Nuclease-resistant Mini-hairpin Structure
Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs. siRNA is recognized and processed by Ago2 and C3PO, endonucleases of the RNA-induced silencing complex (RISC). RISC cleaves passeng...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
Elsevier,
2014-01-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |