Evaluation of the estimation and classification performance of NONMEM when applying mixture model for drug clearance

Abstract Maximum likelihood estimation of parameters involving mixture model is known to have significant and specific patterns of errors. Population pharmacokinetic (PopPK) modeling using NONMEM is no exception. A few relevant studies on estimation and classification performance were done, but a co...

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Main Authors: Ka Ho Hui (Author), Tai Ning Lam (Author)
Format: Book
Published: Wiley, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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