Response to pregabalin and progesterone differs in male and female rat models of neuropathic and cancer pain

• Main Authors: Robert G. Ungard (Author), Yong Fang Zhu (Author), Sarah Yang (Author), Peter Nakhla (Author), Natalka Parzei (Author), Kan Lun Zhu (Author), Gurmit Singh (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cancer pain involves nervous system damage and pathological neurogenesis. Neuropathic pain arises from damage to the nervous system and is driven by ectopic signaling. Both progesterone and pregabalin are neuroprotective in animal models, and there is evidence that both drugs bind to and...