Physiological implications of biased signaling at histamine H2 receptors.

• Autori principali: Natalia eAlonso (Autore), Carlos Daniel Zappia (Autore), Maia eCabrera (Autore), Carlos Alberto Davio (Autore), Carina eShayo (Autore), Federico eMonczor (Autore), Natalia Cristina Fernandez (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2015-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Histamine mediates numerous functions acting through its four receptor subtypes all belonging to the large family of seven transmembrane G-protein coupled receptors (GPCRs). In particular, histamine H2 receptor (H2R) is mainly involved in gastric acid production, becoming a classic pharmacological t...